Myokine Identification Following Acute Exercise

Launched by ROCKEFELLER UNIVERSITY · Jan 15, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Myokine Identification Following Acute Exercise," is investigating how exercise affects the body, particularly focusing on proteins released from muscles that may influence fat tissue. Researchers have discovered that after exercising, many proteins enter the bloodstream, and they want to identify these proteins and understand how they interact with fat tissue. To do this, they will collect blood and fat tissue samples from participants before and after a short exercise session.

To participate in this study, you need to be between 18 and 45 years old, moderately active (exercising at least 30 minutes once a week), and a non-smoker. Some health conditions, like recent surgeries or certain medications, may disqualify you. If you join, you can expect to complete some physical activities, and your blood and fat samples will be analyzed to learn more about the proteins involved in the body’s response to exercise. This research could help us better understand how exercise impacts health, particularly related to body fat.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • passing the PARQ questionnaire (i.e. answering "NO" to all questions)
• • being between the ages of 18-45
• • being moderately active (defined as participating in 30 minutes of recreational activity at least once per week for the past 3 months but no more than 3 times per week)
• • non-smoking
• • free of metabolic or cardiovascular diseases
• Exclusion Criteria:
• • unhealed fractures
• • thrombophlebitis (blood clots)
• • recent surgery of the upper or lower extremities (any surgeries in past 6 months at the ankle or foot, or in the past year at the knee, hip, shoulder or elbow)
• • recent uncontrolled bruising
• • recent muscle, bone or joint damage which interferes with regular physical activity
• • taking part in vigorous physical activity more than 3 times per week
• • any prior sensations of chest pain during exercise.
• • individuals who are pregnant as determined by an on-site pregnancy test
• • individuals who are currently taking exogenous hormones
• • individuals who chronically consume NSAIDS or other anti-inflammatory medication (every day for the previous 3 months)
• • failing the PARQ questionnaire as indicated by answering "YES" to any of the questions
• • Having a BMI \>32
• • Any medical condition that in the opinion of the investigator will confound interpretation of data for analysis.