Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on the Periodontal Health
Launched by BENI-SUEF UNIVERSITY · Jan 23, 2024
Trial Information
Current as of July 07, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how two treatments—Platelet-rich Fibrin (PRF) and Vitamin D injections—affect gum health during orthodontic treatment, which is when braces or other devices are used to straighten teeth. The goal is to see if these treatments can help improve the health of gums in people who need certain dental procedures, specifically those who have specific types of bite issues.
To be part of this study, participants need to be between 18 and 40 years old and have a specific dental condition that requires the removal of certain teeth as part of their orthodontic treatment. It's important that they have good oral hygiene and healthy gums. However, people with active gum disease, poor oral hygiene, or certain health conditions that could affect their teeth or gums won't be eligible. If you join the trial, you'll receive one of the treatments and have regular check-ups to monitor your gum health during the process.
Gender
ALL
Eligibility criteria
- Inclusion criteria:
- • 1. Age: 18- 40 years old.
- • 2. Angle Class I or Class II dental malocclusion that required bilateral maxillary first premolar extraction and upper canine retraction as a part of the treatment plan.
- • 3. Good to fair oral hygiene.
- • 4. Normal probing depth.
- Exclusion criteria:
- • 1. Active periodontal disease.
- • 2. Poor oral hygiene.
- • 3. Systemic diseases or medications that alter bone metabolism or tooth movement.
- • 4. Craniofacial anomalies.
About Beni Suef University
Beni-Suef University is a prominent academic institution in Egypt dedicated to advancing medical research and clinical trials aimed at improving healthcare outcomes. With a strong emphasis on innovation and collaboration, the university fosters a multidisciplinary approach to research, engaging faculty, students, and healthcare professionals in the pursuit of scientific knowledge. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring that all clinical trials conducted under its auspices are designed to enhance patient care and contribute to the global body of medical research. Through its initiatives, Beni-Suef University aims to translate research findings into practical applications that benefit communities locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Banī Suwayf, , Egypt
Patients applied
Trial Officials
Rehab Khalil
Principal Investigator
Faculty of Dentistry Beni Suef University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported