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Search / Trial NCT06224634

The Effect of Anti-IL17 on Airway Hyperresponsiveness and Resistance

Launched by COPENHAGEN UNIVERSITY HOSPITAL, HVIDOVRE · Jan 16, 2024

Trial Information

Current as of June 12, 2025

Recruiting

Keywords

Asthma Interleukin 17 Ankylosing Spondylitis Psoriasis Airway Hyperresponsiveness

ClinConnect Summary

This clinical trial is studying how a specific type of medication called anti-IL-17 might help improve breathing problems in people with asthma. The researchers want to see if this treatment can reduce airway hyperreactivity, which means how sensitive the airways are to triggers that can make it hard to breathe. They will look at how people's breathing changes before and after starting the treatment by using tests to measure airflow in the lungs.

To participate in this study, you need to be an adult who is planning to start anti-IL-17 treatment for skin or joint conditions. However, there are some health conditions that may prevent you from joining, such as being pregnant, having serious heart issues recently, or certain lung function problems. If you qualify and decide to join, you will undergo tests to measure your breathing at the beginning and after starting the treatment. This study could help determine if anti-IL-17 is effective for asthma patients, which could lead to new treatment options in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients planning to start treatment with anti-IL-17 antibodies
  • Exclusion Criteria:
  • Current pregnancy
  • FEV1 \< 1.5L or less than 60% of predicted value expected.
  • Previous anaphylactic shock or severe allergic reaction to medicine
  • Uncontrolled hypertension
  • Myocardial infarction or stroke within the last 3 months
  • Known aortic aneurysm
  • Recent eye surgery or risk of elevated intracranial pressure
  • Treatment with systemic corticosteroids within 6 weeks

About Copenhagen University Hospital, Hvidovre

Copenhagen University Hospital, Hvidovre, is a leading clinical research institution in Denmark, renowned for its commitment to advancing medical knowledge and improving patient care. As a prominent academic hospital affiliated with the University of Copenhagen, it integrates cutting-edge research with clinical practice, fostering innovation in various medical fields. The hospital is dedicated to conducting rigorous clinical trials, ensuring adherence to ethical standards and regulatory guidelines, while prioritizing patient safety and welfare. With a multidisciplinary approach and access to diverse patient populations, Copenhagen University Hospital, Hvidovre plays a vital role in translating research findings into effective treatments and therapies.

Locations

Hvidovre, Capital Region, Denmark

Patients applied

0 patients applied

Trial Officials

Jonas A Baekdal, MD

Principal Investigator

University hospital, Hvidovre

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported