Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Launched by CENTRO UNIVERSITÁRIO AUGUSTO MOTTA · Jan 23, 2024
Trial Information
Current as of September 12, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This trial is studying whether wearing compression socks while running can reduce muscle soreness after running in distance runners. It’s a randomized, double-blind, sham-controlled crossover study, meaning each participant tries both conditions (real compression socks and placebo socks) in different sessions, with a 7–10 day break in between. The main thing they’ll look at is how sore the lower legs feel 24 hours after running, using a 0–100 pain scale. They’ll also measure soreness right after the run and at 48 hours, plus how recovered participants feel, how hard the running was, mood during and after, and average heart rate.
About who can participate: adults 18–50 who run regularly (at least 3 times a week and at least 10 km per week in the past six months) and who haven’t run more than 42 km in the last month. Exclusions include pregnancy, recent leg fractures or surgeries, history of blood clots or kidney disease, or a running-related injury in the last six months. The study is being conducted in Rio de Janeiro, Brazil, led by Gustavo Telles at Centro Universitário Augusto Motta. Enrollment is ongoing, and the study is expected to finish in July 2025. The socks are made to look the same to keep participants and researchers unaware of which type is being worn.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Run consistently in the last six months (at least three times a week and at least 10 kilometres per week);
- • Runners who did not run further than 42 kilometres in the last month.
- Exclusion Criteria:
- • Pregnancy;
- • Any lower limbs fracture in the last 12 months;
- • History of lower limb arthroplasty or osteotomy, previous venous thrombosis, kidney disease;
- • Any running-related injury in the last six months. A running-related injury will be considered the presence of lower limb pain that caused restriction, stoppage of running (distance, speed, duration, or training) for at least seven days or three consecutive scheduled training sessions or the need for a health professional treatment
About Centro Universitário Augusto Motta
Centro Universitário Augusto Motta (CEHAM) is a distinguished higher education institution in Brazil, dedicated to advancing medical research and clinical trials. With a strong emphasis on innovation and scientific excellence, CEHAM fosters an environment that encourages collaboration among health professionals, researchers, and students. The institution is committed to conducting rigorous clinical studies that contribute to the enhancement of healthcare practices and the development of new therapies. CEHAM’s multidisciplinary approach and adherence to ethical standards ensure that its clinical trials are conducted with the utmost integrity, aiming to improve patient outcomes and drive forward the frontiers of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rio De Janeiro, Brazil
Patients applied
Trial Officials
Leandro AC Nogueira, PhD
Study Chair
Centro Universitário Augusto Motta
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported