Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory Distress Syndrome
Launched by TANTA UNIVERSITY · Jan 17, 2024
Trial Information
Current as of June 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how two different ways of giving a treatment called hypertonic saline (a salt solution) can help patients with a serious lung condition known as Acute Respiratory Distress Syndrome (ARDS). Specifically, the researchers want to find out if giving hypertonic saline through a nebulizer (a device that turns liquid medicine into a mist) is more effective than giving it through an intravenous (IV) injection. This study is currently looking for participants between the ages of 21 and 60 who have mild to moderate ARDS.
If you or a family member are considering participation, you would need to meet certain criteria, such as having a specific level of oxygen in your blood. However, some people may not be eligible, including those with certain cancers, advanced kidney or heart problems, or high sodium levels in their blood. If you join the trial, you can expect to receive either treatment and be monitored closely by the medical team to see how well it works for you. This study aims to improve the care and outcomes for patients suffering from ARDS.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age from 21 to 60 years old.
- • Both sexes.
- • Patients with mild and moderate ARDS whose PaO2/FiO2 ratio ≥ 150 according to the Berlin definition of Acute Respiratory Distress Syndrome.
- Exclusion Criteria:
- • Refusal to participate in the study.
- • Malignancy.
- • Patients on chemotherapy.
- • Decompensated renal, hepatic and cardiac disease.
- • Patients with hypernatremia whose serum Na above 155 mEq/L.
- • Patients with ARDS whose PaO2/FiO2 ratio \> 150.
About Tanta University
Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tanta, El Gharbia, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported