Search / Trial NCT06227559

The Role of Some Hematological Parameters in Juvenile Systemic Lupue Erythematosus

Launched by ASSIUT UNIVERSITY · Jan 25, 2024

Trial Information

Current as of December 22, 2024

Not yet recruiting

Keywords

ClinConnect Summary

Juvenile systemic lupus erythematosus is an autoimmune disorder with multisystem involvement, leading to inflammatory damage to the joints, kidney, central nervous system, and hematopoietic system. Although the prevalence rate of juvenile systemic lupus erythematosus in a developing country is not known, as per literature the female-to-male ratio rises from 4.5 : 1 in adolescence to 8--12 : 1 in adult-onset patients.

- The full mechanism of SLE is still unknown however, production of autoantibodies and immune complex deposition with subsequent infiltration of neutrophils, hyper-activation ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Age at enrollment ≤18 years old.
  • 2. Both sexes
  • 3. The Patients should be diagnosed as jSLE, according to 2019 European league against rheumatism (EULAR)/ American college of rheumatology (ACR) SLE classification criteria, or the previous ACR 1997 SLE classification criteria.
  • Exclusion criteria:
  • 1. Patients with autoimmune diseases other than j SLE
  • 2. Patients not fulfilling the criteria for diagnosis of SLE
  • 3. Active infections.
  • 4. Malignancies.
  • 5. Lymphoproliferative disorders.
  • 6. Hematologic diseases
  • 7. Hepatosplenic diseases and diabetic nephropathy

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

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Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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