Search / Trial NCT06228573

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Launched by MCMASTER UNIVERSITY · Jan 18, 2024

Trial Information

Current as of December 30, 2024

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help people with knee osteoarthritis, a condition that causes pain and can limit movement. The researchers are testing a combination of two treatments: Transcranial Direct Current Stimulation (tDCS), which is a non-invasive technique that gently stimulates the brain to help manage pain, and yoga, which promotes overall well-being. The goal is to see if this combination can effectively reduce pain and improve how the nervous system functions in people suffering from knee arthritis.

To participate in this study, you need to be at least 45 years old and living in certain areas of Canada, like Sherbrooke, Quebec, or Hamilton and London, Ontario. You should have been diagnosed with knee osteoarthritis or have joint pain related to movement. Participants will be randomly assigned to receive either the real tDCS treatment combined with yoga or a fake version of the treatment with yoga. Throughout the study, researchers will monitor pain levels and other related measures to see how well this new approach works. If you have certain medical conditions or have had recent treatments, you may not be eligible to join. This trial aims to find better ways to manage knee arthritis pain, which could greatly improve the quality of life for many.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • community dwelling adults from Sherbrooke, Quebec, Hamilton and London, Ontario fulfilling the NICE criteria for KOA
  • ≥45 years of age
  • Diagnosis of Knee osteoarthritis OR
  • Having movement-related joint pain with either no morning knee stiffness or stiffness of 30 minutes or less AND
  • Experiencing an average pain intensity of ≥3 /10 in the past month
  • Exclusion Criteria:
  • Systemic inflammatory arthritis.
  • Any knee injection in the past 3 months.
  • Inability to independently get up and down from the floor.
  • Lower limb trauma or surgery within the last 6 months.
  • Current participation in another OA clinical trial.
  • Use of mobility aids.
  • Currently receiving care for KOA pain (e.g., physiotherapy).
  • Planned absences exceeding 1 week.
  • Contraindications to transcranial direct current stimulation (tDCS) such as neurological or neuropsychiatric conditions.
  • History of brain surgery or tumor.
  • Metallic implants.
  • Epilepsy or history of substance abuse or dependence.
  • Cochlear or ocular implant.
  • Presence of a pacemaker or cardiac defibrillator.
  • Eczema on the scalp.

Trial Officials

Lisa Carlesso, PhD

Principal Investigator

McMaster University

About Mcmaster University

McMaster University, a leading research institution located in Hamilton, Ontario, Canada, is renowned for its innovative approach to education and its commitment to advancing healthcare through rigorous clinical research. The university's diverse research programs are supported by a multidisciplinary team of experts dedicated to improving patient outcomes and public health. With a strong emphasis on evidence-based medicine, McMaster University actively engages in clinical trials that explore new therapies, interventions, and health technologies, fostering collaboration among researchers, healthcare professionals, and industry partners to translate findings into real-world applications.

Locations

London, Ontario, Canada

Sherbrooke, Quebec, Canada

Hamilton, Ontario, Canada

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0