Search / Trial NCT06228573

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Launched by MCMASTER UNIVERSITY · Jan 18, 2024

Trial Information

Current as of October 04, 2024

Not yet recruiting

Keywords

Description

Background: 'Omnipresent' is a common word that people living with knee osteoarthritis (KOA) use to describe the associated pain, with its unpredictability causing physical, social and emotional disruption. For many, KOA pain leads to limited mobility, reduced quality of life and increased healthcare costs KOA pain and its mechanisms are known to be complex, with alterations in nervous system signaling (ANSS) leading to persistent pain, and treatment failure to guideline-based care. Unfortunately, there is a lack of effective conservative treatments for KOA pain, including exercise which e...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * community dwelling adults from Sherbrooke, Quebec, Hamilton and London, Ontario fulfilling the NICE criteria for KOA
  • * ≥45 years of age
  • * Diagnosis of Knee osteoarthritis OR
  • * Having movement-related joint pain with either no morning knee stiffness or stiffness of 30 minutes or less AND
  • * Experiencing an average pain intensity of ≥3 /10 in the past month
  • Exclusion Criteria:
  • * Systemic inflammatory arthritis.
  • * Any knee injection in the past 3 months.
  • * Inability to independently get up and down from the floor.
  • * Lower limb trauma or surgery within the last 6 months.
  • * Current participation in another OA clinical trial.
  • * Use of mobility aids.
  • * Currently receiving care for KOA pain (e.g., physiotherapy).
  • * Planned absences exceeding 1 week.
  • * Contraindications to transcranial direct current stimulation (tDCS) such as neurological or neuropsychiatric conditions.
  • * History of brain surgery or tumor.
  • * Metallic implants.
  • * Epilepsy or history of substance abuse or dependence.
  • * Cochlear or ocular implant.
  • * Presence of a pacemaker or cardiac defibrillator.
  • * Eczema on the scalp.

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Hamilton, Ontario, Canada

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0