Search / Trial NCT06228729

Association Between EEG Changes and Hormonal Response to Tracheal Intubation and Surgical Stimulation

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Jan 18, 2024

Trial Information

Current as of October 09, 2024

Not yet recruiting

Keywords

Description

This study aims to investigate the relationship between changes in EEG patterns and stress hormone levels in patients undergoing open abdominal surgery under general anesthesia when subjected to endotracheal intubation and surgical incision stimuli. Hormone measurements (cortisol, ACTH) are taken at four time points: before endotracheal intubation (T1), one minute after intubation (T2), and one minute after surgical incision (T3). The investigators evaluate the correlation between hormone levels (cortisol, ACTH) and EEG band power changes (alpha, beta, delta) before and after endotracheal ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * 1) Patients scheduled to undergo open abdominal surgery under general anesthesia with endotracheal intubation.
  • * 2) Patients requiring invasive blood pressure monitoring during surgery
  • Exclusion Criteria:
  • * 1) Patients transferred to the intensive care unit after surgery
  • * 2) Surgery duration of less than one hour
  • * 3) Patients with neurological underlying conditions
  • * 4) Patients on chronic use of psychotropic medications and opioid drugs
  • * 5) Emergency surgery

About Seoul National University Hospital

Seoul National University Hospital (SNUH) is a leading medical institution in South Korea, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, SNUH integrates cutting-edge scientific inquiry with patient-centered care, facilitating the development of novel therapies and treatment protocols. The hospital boasts a diverse range of specialized departments and a robust infrastructure for conducting clinical studies, ensuring rigorous adherence to ethical standards and regulatory compliance. By fostering collaboration among multidisciplinary teams, SNUH aims to contribute significantly to global medical advancements and improve patient outcomes.

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Trial launched

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Estimated completion

Not reported

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