Association Between EEG Changes and Hormonal Response to Tracheal Intubation and Surgical Stimulation

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Jan 18, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how certain brain activity changes, measured by a test called an EEG, relate to hormonal responses during procedures like tracheal intubation (a way to help patients breathe during surgery) and surgical incisions in patients undergoing abdominal surgery. The researchers want to better understand how these two factors interact after patients receive general anesthesia, which puts them into a deep sleep during surgery.

To participate in this study, patients need to be scheduled for open abdominal surgery that requires general anesthesia and invasive blood pressure monitoring. However, certain patients will not be eligible, such as those who will need to go to intensive care after surgery, have surgery lasting less than an hour, or have specific neurological conditions. If someone qualifies for the study, they can expect to have their EEG monitored during the surgery to see how their brain activity and hormone levels change. This research could help improve patient care during surgeries in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1) Patients scheduled to undergo open abdominal surgery under general anesthesia with endotracheal intubation.
• • 2) Patients requiring invasive blood pressure monitoring during surgery
• Exclusion Criteria:
• • 1) Patients transferred to the intensive care unit after surgery
• • 2) Surgery duration of less than one hour
• • 3) Patients with neurological underlying conditions
• • 4) Patients on chronic use of psychotropic medications and opioid drugs
• • 5) Emergency surgery