Multimodal Musical Stimulation for Healthy Neurocognitive Aging

Launched by NORTHEASTERN UNIVERSITY · Jan 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of music can help improve working memory in healthy older adults. Researchers want to see if listening to music in a specific way can positively affect brain function as we age. The trial is looking for participants aged 65 to 74, as well as younger adults, who meet certain health criteria. For example, participants should have normal or corrected vision and only mild hearing loss. They should not have any serious neurological or psychiatric conditions that could affect their memory or how they respond to music.

If you join this study, you will take part in activities that assess your memory and brain activity while listening to music. The trial is designed to be safe and will involve comparing the effects of real music stimulation to a control group that listens to non-stimulating sounds. This research is important because it could lead to new ways to support brain health and potentially reverse cognitive decline associated with aging.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • normal or corrected-to-normal vision
• • no more than mild hearing loss
• • no recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music.
• Exclusion Criteria:
• • moderate or severe hearing loss (40+ dB)
• • visual impairment (including color blindness) that cannot be corrected with glasses or contacts
• • recently changed dosage of cholinesterase inhibitors or psychotropic medication
• • recent history of psychotic or schizophrenic episodes
• • major neurologic diagnosis or other condition that might impair cognition or confound assessments (dementia, ADRD; Parkinson's disease, stroke, brain injury, epilepsy, or recent cardiovascular or neurovascular event)
• • recent history of serious physical trauma or diagnosis of serious chronic health condition requiring medical treatment and monitoring .