Spinal Cord Stimulation for the Treatment of Pain in Chronic Pancreatitis
Launched by AALBORG UNIVERSITY HOSPITAL · Jan 19, 2024
Trial Information
Current as of July 01, 2025
Completed
Keywords
ClinConnect Summary
Chronic pancreatitis (CP) is a condition causing considerable morbidity, with nearly 0.5 million new cases emerging in Europe every year. It is characterized by a fibro-inflammatory process that progressively damages the pancreas. As the disease advances, most patients experience exocrine pancreatic insufficiency and diabetes, but the most debilitating aspect is severe abdominal pain, which affects about 70% of patients. The pain's origins in CP are complex, typically associated with pancreatic inflammation, ductal obstruction, damage to pancreatic nerves due to inflammation and fibrosis, a...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Chronic pancreatitis according to the M-ANNHEIM criteria
- • Chronic abdominal pain (pain 3=3days per week in at least 3 months)
- • Pain insuficiently treated with patients ussual analgesic treatment
- • Patients with signs of obstruction of the pancreatic duct due to a stricture or stone have to undergo endoscopic or surgical decompression prior to enrolment
- Exclusion Criteria:
- • Patients suffering from painful conditions other than chronic pancreatitis that made them unable to distinguish the pain associated with chronic pancreatitis
- • Patients with ongoing alcohol abuse and illegal drug dependencies
About Aalborg University Hospital
Aalborg University Hospital is a leading healthcare institution in Denmark, renowned for its commitment to advancing medical research and patient care. As a prominent clinical trial sponsor, the hospital actively engages in innovative studies aimed at improving health outcomes across various medical disciplines. With a focus on collaboration and interdisciplinary approaches, Aalborg University Hospital leverages its state-of-the-art facilities and expertise to conduct rigorous clinical trials, ensuring adherence to the highest ethical standards and regulatory requirements. The institution is dedicated to fostering a culture of research excellence, contributing valuable insights to the medical community and enhancing treatment options for patients.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Aalborg, , Denmark
Patients applied
Trial Officials
Helga A Gulisano, MD
Principal Investigator
Aalborg University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported