Search / Trial NCT06230380

Autofluorescence in Surgery for Primary Hyperparathyroidism

Launched by AARHUS UNIVERSITY HOSPITAL · Jan 20, 2024

Trial Information

Current as of October 08, 2024

Recruiting

Keywords

Description

Parathyroidectomy (PTX) is the only curative treatment for primary hyperparathyroidism (PHPT).1 Prior to surgery, imaging is performed to determine the anatomical location of pathological parathyroid gland (PTGs). Usually two independent localizing imaging methods are used, e.g. sestamibi scintigraphy and neck ultrasound. Additional imaging modalities may be added, e.g. PET/CT. In case of concordant imaging results, a selective/focused PTX may be performed with removal of the identified pathological gland. If imaging is negative or non-concordant, an exploratory parathyroidectomy (ePTX) is ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Age\>18 years and able to give informed consent.
  • * A diagnosis of PHPT.
  • * Planned exploratory PTX with ioPTH measurement.
  • Exclusion Criteria:
  • * Concordant high-confidence imaging; planned focused/selective PTX
  • * Previous thyroid or parathyroid surgery.
  • * Planned simultaneous thyroid surgery.
  • * MEN, lithium induced hyperparathyroidism.
  • * eGFR \< 30.
  • * Kidney transplant.

About Aarhus University Hospital

Aarhus University Hospital is a leading research institution in Denmark, dedicated to advancing medical science and improving patient care through innovative clinical trials. As a key sponsor of clinical research, the hospital integrates cutting-edge technology and multidisciplinary expertise to conduct studies that address critical health challenges. With a commitment to ethical standards and patient safety, Aarhus University Hospital collaborates with a diverse network of academic and industry partners, ensuring that its research initiatives contribute to the global body of medical knowledge and enhance treatment options for patients.

Locations

Aarhus, , Denmark

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0