MARIMPACH : Contribution of High-resolution Manometry With Impedancemetry for the Evaluation of Esophageal Clearance in Achalasia

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Jan 19, 2024

Keywords

ClinConnect Summary

The MARIMPACH trial is studying how well two different tests measure the ability of the esophagus to clear food and liquids in patients with a condition called achalasia. Achalasia makes it hard for the esophagus to move food down to the stomach. The trial compares a newer test called high-resolution manometry with impedancemetry (HRiM) to a traditional test called timed barium esophagogram (TBE). Both tests are used to see how effective a treatment called POEM (Peroral Endoscopic Myotomy) is for improving esophageal function.

Patients who are treated with POEM at Bordeaux University Hospital between October 2020 and September 2024 may be eligible to join the study. To participate, they should not have had a primary failure of the POEM procedure, and they need to complete certain assessments before and after the treatment. Those who join the trial can expect to undergo these tests to help researchers understand how well each method works in measuring esophageal clearance. This study aims to improve the care for people with achalasia by identifying the best ways to assess treatment outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The patients included are all patients treated by POEM at Bordeaux University Hospital between October 2020 and September 2024.
• Exclusion Criteria:
• • Primary POEM failure, lost to follow-up, absence of completion of the ES, TBE or HRiM pre or post poem at 3 months.