Mechanomyography Reloaded? A Randomized Prospective Agreement Study

Launched by UNIVERSITY HOSPITAL ULM · Jan 19, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Mechanomyography Reloaded? A Randomized Prospective Agreement Study," is investigating a new device called mechanomyography (MMG) that measures muscle strength during surgery. This device aims to improve how doctors monitor muscle function when using medications that relax muscles, ensuring patients recover fully after anesthesia. The study will compare the effectiveness of this new device to the current standard method, which uses electromyography (EMG) to monitor muscle activity.

To be eligible for this trial, participants must be at least 18 years old and scheduled for non-heart-related surgery that requires general anesthesia and muscle relaxation. They should also be able to have both arms accessible during the surgery. However, individuals with certain conditions, such as allergies to muscle relaxants or neuromuscular diseases, or those who are pregnant or recently postpartum, cannot participate. If eligible, participants can expect to be involved in comparing the new MMG device to the traditional method during their surgery, which could help improve monitoring techniques in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age ≥ 18 years
• • ASA \< 3
• • scheduled for non-cardiac surgery requiring general anaesthesia and neuromuscular blockade for optimisation of surgical conditions
• • positioning during surgery with intraoperative access to both arms
• Exclusion Criteria:
• • allergy to muscle relaxants and reversal agents
• • neuromuscular disease
• • procedure is scheduled outside the operating room
• • need of endotracheal intubation prior to surgery
• • need of rapid sequence induction
• • pregnancy, breastfeeding or 30 days postpartum
• • surgical procedure or examination findings which are a contraindication for a supraglottic airway device
• • employee of the investigator or study site directly involved in this study or other studies under the direction of the investigator or study site
• • family member of the investigator
• • custodial accommodation
• • alcohol or drug abuse
• • patients with preceding injuries impairing muscle or nerve function of the arm
• • Participation in other studies with investigational drugs or devices within 4 weeks prior to screening or missing agreement not to participate in any other study at the same time or within a period of one month after the MEMORY study