Mechanomyography Reloaded? A Randomized Prospective Agreement Study

Launched by UNIVERSITY HOSPITAL ULM · Jan 19, 2024

Keywords

ClinConnect Summary

The MEMORY trial is a randomized clinical agreement study which will prospectively enrol thirty ASA 1 or 2 patients ≥ 18 years scheduled for non-cardiac surgery requiring general anaesthesia and neuromuscular blockade for optimisation of surgical conditions. The patient's neuromuscular function is measured on one hand with MMG and the other hand with EMG in a randomised fashion. Additionally, randomisation will be stratified the domination of one hand.

In the MEMORY trial we will test the hypothesis, that a newly developed MMG sensor provides not less reliable measurements of neuromuscular...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age ≥ 18 years
• • ASA \< 3
• • scheduled for non-cardiac surgery requiring general anaesthesia and neuromuscular blockade for optimisation of surgical conditions
• • positioning during surgery with intraoperative access to both arms
• Exclusion Criteria:
• • allergy to muscle relaxants and reversal agents
• • neuromuscular disease
• • procedure is scheduled outside the operating room
• • need of endotracheal intubation prior to surgery
• • need of rapid sequence induction
• • pregnancy, breastfeeding or 30 days postpartum
• • surgical procedure or examination findings which are a contraindication for a supraglottic airway device
• • employee of the investigator or study site directly involved in this study or other studies under the direction of the investigator or study site
• • family member of the investigator
• • custodial accommodation
• • alcohol or drug abuse
• • patients with preceding injuries impairing muscle or nerve function of the arm
• • Participation in other studies with investigational drugs or devices within 4 weeks prior to screening or missing agreement not to participate in any other study at the same time or within a period of one month after the MEMORY study

Trial Officials