Search / Trial NCT06230705

Community Intervention to Improve CVD Risk Factor Control in Young American Indians

Launched by UNIVERSITY OF OKLAHOMA · Jan 19, 2024

Trial Information

Current as of December 22, 2024

Not yet recruiting

Keywords

Elevated Cholesterol Diabetes Mellitus Cardiovascular Disease American Indian Young Adult

ClinConnect Summary

Cardiovascular disease (CVD) incidence in American Indians is more than two-fold higher than the age-matched United States (US) population, and significantly associated with elevated lipids/lipoproteins and glucose levels. Through systematic surveillance conducted by the Strong Heart Study (SHS), the largest and longest running study of CVD in American Indians, we report that elevated lipid/lipoprotein prevalence for participants \<20, 20-29, and 30-39 years old was 55.2%, 73.6%, and 78.0%, respectively. In addition, we report that American Indians under 40 years old with elevated LDL chole...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • American Indians
  • 18-39 years old
  • Members of the tribal communities that participate in the Strong Heart Study in southwestern Oklahoma
  • Only one person per household will be eligible
  • Exclusion Criteria:
  • Are unwilling or unable to follow the intervention, which includes modifying current nutritional intake and participating in the proposed physical activity program
  • Are taking lipid-/lipoprotein-lowering or diabetes medication
  • Are already participating in a diabetes or CVD risk factor reduction program
  • Are pregnant or plan to become pregnant in the next 18 months
  • Are not English speaking
  • Are institutionalized
  • Have underlying disease with a life-expectancy of less than 2 years (e.g., cancer or end stage renal disease).

Trial Officials

Jessica A Reese, PhD

Principal Investigator

University of Oklahoma

About University Of Oklahoma

The University of Oklahoma, a leading research institution, is dedicated to advancing healthcare through innovative clinical trials and research initiatives. With a robust network of interdisciplinary experts and state-of-the-art facilities, the university fosters an environment that promotes scientific discovery and the development of new treatments. Its commitment to patient-centered research ensures that clinical trials not only adhere to the highest ethical standards but also aim to address pressing health challenges. By collaborating with various stakeholders, including industry partners and healthcare providers, the University of Oklahoma seeks to translate research findings into tangible benefits for communities, ultimately enhancing the quality of care and improving health outcomes.

Locations

Oklahoma City, Oklahoma, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0