Speech Pattern Evaluation and Analysis for Knowledge of AD

Launched by UNIVERSITY OF WISCONSIN, MADISON · Jan 19, 2024

Keywords

ClinConnect Summary

This clinical trial, called "Speech Pattern Evaluation and Analysis for Knowledge of AD," is looking at how changes in speech can help us understand thinking skills in people who might be at risk for Alzheimer's disease and related conditions. By studying how speech patterns change, researchers hope to find new ways to detect early signs of Alzheimer's. Participants will be asked to use an iPad to record their speech and fill out a survey from the comfort of their homes, and the study will last for about three years.

To be eligible for this study, participants should be between 40 and 80 years old, and either have normal thinking skills or mild cognitive impairment (MCI). They must also be part of the Wisconsin Alzheimer's Disease Research Center (W-ADRC) or the Wisconsin Registry for Alzheimer's Prevention (WRAP) programs. It’s important to note that individuals with a diagnosis of dementia or certain neurological conditions, as well as those who have trouble speaking, cannot participate. This study is currently recruiting participants and aims to help improve our understanding of Alzheimer's disease through speech analysis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Must be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or in the Wisconsin Registry for Alzheimer's Prevention (WRAP)
• • Cognitively unimpaired or have a diagnosis of Mild Cognitive Impairment (MCI)
• • Ages 40-80 years
• • Completion of a W-ADRC or WRAP study visit within the past or upcoming 12 months
• • Have provided W-ADRC or WRAP with blood plasma Alzheimer's Disease
• Exclusion Criteria:
• • Not actively enrolled in W-ADRC or WRAP
• • Diagnosis of dementia
• • Impaired capacity or unwilling to consent
• • Major neurological conditions
• • Speech disorders