Development and Validation of a PSN-AI Prediction Model

Launched by SIXTH AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Jan 26, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new model called PSN-AI, which aims to predict how long patients with colorectal cancer and peritoneal metastases (cancer that has spread to the lining of the abdomen) might survive. The researchers believe that by looking at specific factors in a patient's tumors, they can better understand and classify the different ways this type of cancer affects survival. This information is important because it can help doctors make more personalized treatment plans for patients.

To be eligible for this trial, participants need to have a confirmed diagnosis of colorectal cancer that has spread to the peritoneum but not to other parts of the body like the liver or lungs. They must also be candidates for surgery to remove the cancer. The study is currently recruiting participants aged between 65 and 74 years. If you join this trial, you can expect to undergo tests and assessments related to your condition, and you'll be contributing to important research that may improve future treatments for colorectal cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Histological proof of synchronous peritoneal metastases of a nonappendiceal colorectal adenocarcinoma.
• • Resectable disease determined by computed tomography (CT) and a peritoneal cancer index (PCI) of ≤20 at diagnostic laparoscopy or laparotomy;
• • No evidence of systemic (e.g. liver, lung) colorectal metastases within three months prior to enrolment;
• • Undergoing cytoreduction surgery for synchronous peritoneal metastasis from colorectal cancer.
• Exclusion Criteria:
• • Combined with other types of malignant tumors.