Search / Trial NCT06231628

Imaging Guided Cementoplasty for Pelvic Bone Metastasis

Launched by ASSIUT UNIVERSITY · Jan 26, 2024

Trial Information

Current as of October 04, 2024

Not yet recruiting

Keywords

Cementoplasty Metastasis Percutaneous Pelvis

Description

Bone metastasis (BM) is the major cause of morbidity in patients with cancer. After lungs and liver, bone is the third most common site of metastatic disease. Prostate and breast cancers are responsible for the majority of bone metastases (up to 70%), followed by thyroid, lung, urinary bladder, and renal cancers, and finally melanoma. The incidence of bone metastasis is approximately 100,000 new cases per year in the united states and is increasing. Bone metastasis could result in skeletal-related events, including pain, pathological fracture, hypercalcemia, and nerve and visceral compressi...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. refractory pain and/or gait disturbance caused by pelvic bone metastasis, did not respond to conservative treatment.
  • 2. osteolytic lesion (in predominance) suitable for the pain.
  • 3. limited life expectancy (less than 3 years) or stopping medical treatment
  • Exclusion Criteria:
  • There are no absolute contraindications for the procedure; however, the relative contraindications are:
  • 1. patients in poor condition with an expected survival period of less than 3 months.
  • 2. patients with stable course, with long life expectancy (more than 3 years) or those considered candidates for major pelvic surgery including tumor removal and hip arthroplasty.
  • 3. presence of bone destruction with soft tissue mass contaminating important organs, nerves and blood vessels (improvement is not expected).
  • 4. Patients refusing to give a written consent to the study protocol.

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0