Search / Trial NCT06231849

Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate.

Launched by ASSIUT UNIVERSITY · Jan 27, 2024

Trial Information

Current as of October 07, 2024

Not yet recruiting

Keywords

Gut Microbiota . Opioid Use

Description

Addiction is defined as a chronic, relapsing disorder characterized by compulsive drug seeking and use despite adverse consequences. Pathological substance use disorders represent a major public health crisis with limited effective treatment options. Although the gut and brain are separate organs, they communicate with each other via trillions of intestinal bacteria that collectively make up one's gut microbiome. Findings from both humans and animals support a critical role of gut microbes in regulating brain function, mood, and behavior. Gut bacteria influence neural circuits that are nota...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. Clinical and laboratory diagnosis of substance missuse.
  • 2. Must be encountering withdrawal symptoms for the first time.
  • Exclusion Criteria:
  • 1. An intelligence quotient (IQ) below 70.
  • 2. Gastrointestinal diseases.

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0