Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries
Launched by TAIPEI HOSPITAL, MINISTRY OF HEALTH AND WELFARE · Jan 22, 2024
Trial Information
Current as of July 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of physical therapy and platelet-rich plasma (PRP) injections on people with injuries to the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) in the knee. These ligaments are important for keeping your knee stable and functioning properly. Researchers want to see how these treatments can help improve pain and mobility in patients who have had partial tears in these ligaments, without them having had any previous surgery for their injuries.
To participate in the trial, you need to be between 18 and 80 years old and have an MRI that shows a partial tear of the ACL or PCL. You should not have had any knee surgeries before this injury, and you must be able to participate in physical activities. If you join, you'll receive treatment based on what you and your doctor decide together. You'll also undergo some tests to assess your knee's strength and movement, both at the beginning and again two months later, to see how well the treatments are working. This study is currently looking to recruit participants, so it’s a great opportunity to potentially benefit from new therapies while contributing to important research.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age between 18 to 80 years old.
- • 2. Magnetic Resonance Imaging (MRI) shows partial tearing of the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL), possibly combined with injuries to the medial collateral ligament (MCL) or meniscus.
- • 3. No surgical treatment has been undergone.
- Exclusion Criteria:
- • 1. Had knee joint diseases or undergone knee joint surgery before the injury.
- • 2. Surgical intervention is required for severe damage to knee joint ligaments, meniscus, or articular tissues, such as complete rupture of lateral ligaments or full-thickness cartilage injuries.
- • 3. Suffers from diseases affecting physical activity function, such as stroke or nerve damage.
About Taipei Hospital, Ministry Of Health And Welfare
Taipei Hospital, under the Ministry of Health and Welfare of Taiwan, is a leading clinical research institution dedicated to advancing healthcare through innovative medical research and trials. With a commitment to enhancing patient outcomes and public health, the hospital integrates state-of-the-art facilities and a multidisciplinary team of experts to conduct rigorous clinical studies across various therapeutic areas. As a sponsor, Taipei Hospital prioritizes ethical standards, patient safety, and scientific integrity, contributing valuable insights to the global medical community and fostering collaboration to address pressing health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
New Taipei City, Roc, Taiwan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported