Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty

Launched by POZNAN UNIVERSITY OF MEDICAL SCIENCES · Jan 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two medications, dexamethasone and dexmedetomidine, to see how they affect pain management after hip surgery, specifically during a type of nerve block called an erector spinae plane block (ESPB). The goal is to find out which medication helps the nerve block last longer and provides better pain relief for patients undergoing hip arthroplasty, a surgical procedure to replace a damaged hip joint.

To participate in this study, you must be at least 18 years old and scheduled for hip surgery. The study is open to people of all genders and those who are generally healthy (with a physical status of ASA 1, 2, or 3). However, if you have certain health issues like severe liver or kidney problems, a history of opioid abuse, or specific neurological conditions, you may not be eligible. If you join the trial, you can expect to receive one of the two medications during your procedure, and researchers will monitor your pain levels and how long the pain relief lasts afterward. This study is currently recruiting participants, and your involvement could help improve pain management strategies for future hip surgery patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients undergoing primary hip arthroplasty
• • aged \>18 years and \<100 years
• • ASA physical status 1, 2 or 3.
• Exclusion Criteria:
• • if they refused to participate,
• • had a history of opioid abuse,
• • had an infection of the site of needle puncture,
• • were less than 18 years of age,
• • were postponed as having ASA 4 or 5,
• • had an allergy to any of the drugs used in the study,
• • renal failure (estimated glomerular filtration rate \<15ml/min/1.73m2),
• • liver failure,
• • known or suspected coagulopathy,
• • pre-existing anatomical or neurological disorders in the lower extremities,
• • intellectual disability with problems in pain evaluation,
• • severe psychiatric illness.