Search / Trial NCT06233968

Using Data Science To Center Patient Perspectives in Mechanism Discovery

Launched by CAMBRIDGE HEALTH ALLIANCE · Jan 23, 2024

Trial Information

Current as of October 07, 2024

Recruiting

Keywords

Natural Language Processing Machine Learning Internal Family Systems

Description

Demand for cost-effective, novel, scalable trauma-focused interventions is high. Prevalence rates of posttraumatic stress disorder (PTSD) and Complex PTSD in US community mental health clinics are estimated to be as high as 50%. Yet response heterogeneity to PTSD interventions remains high, with non-response rates reaching 50-60% and dropout rates for traditional interventions (i.e., cognitive behavioral, exposure therapies) at 30-40%. Moreover, research populations in typical stepwise, efficacy-driven clinical research trials are often characterized by strict exclusion criteria and low rep...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Must be enrolled in the clinical service offering online PARTS group and approved and confirmed to start by the clinical team.
  • Have sufficient English fluency and literacy skills to understand the consent process, procedures and questionnaires and have the ability to provide written informed consent.
  • Have access to the internet and an electronic device with adequate data capacity; to complete questionnaires online and participate in two online video interviews.
  • Must be willing to complete online computerized assessments both at baseline and post-intervention; and participate in two, one-hour videotaped interviews one at baseline and one 2-4 weeks post-intervention.
  • Exclusion Criteria:
  • Inability to complete an informed consent assessment AND/OR inability to complete baseline study assessment procedures (due to cognitive deficit, non-proficiency in English literacy, or any other reason).
  • Expected medical hospitalization in 24 weeks from the date of enrollment.
  • Expected incarceration in 24 weeks from the date of enrollment.
  • Individuals who are pregnant with a due date within 24 weeks after study consent.
  • Insufficient internet connection to conduct online interviews or computerized assessments.

About Cambridge Health Alliance

Cambridge Health Alliance (CHA) is a prominent healthcare system in Massachusetts, dedicated to providing high-quality, community-centered health services. As a clinical trial sponsor, CHA leverages its robust research infrastructure and commitment to innovation to advance medical knowledge and improve patient outcomes. With a focus on diverse populations, CHA conducts clinical trials across various therapeutic areas, ensuring that research is inclusive and reflective of the community it serves. The organization is committed to ethical standards and regulatory compliance, fostering collaboration among healthcare professionals, researchers, and participants to drive advancements in clinical care.

Locations

Malden, Massachusetts, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0