Search / Trial NCT06234046

Rifaximin as a Prophylaxis of Spontaneous Bacterial Peritonitis in Comparison With Ciprofloxacin

Launched by AIN SHAMS UNIVERSITY · Jan 29, 2024

Trial Information

Current as of October 07, 2024

Completed

Keywords

Description

This randomized controlled trial included 80 Egyptian patients diagnosed with cirrhotic liver disease and ascites just recovered from SBP attack grouped into two groups as; * Group (1) included 40 cases received Rifaximin as 550 mg twice daily dose for a six-months period. * Group (2) included 40 cases received Ciprofloxacin as 750 mg once weekly dose for a six-months period. The included cases were collected from hepatology outpatient clinic and inpatient department at Ain shams University hospital between May 2023 and November 2023 after the scientific ethical committee approval. A writ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * cirrhotic liver disease patients with ascites just recovered from SBP attack.
  • * Must be able to swallow tablets
  • Exclusion Criteria:
  • * Cases with metastatic HCC.
  • * patients with drug allergy from Ciprofloxacin or Rifaximin.
  • * those having ascites secondary to other causes rather than liver cirrhosis.
  • * those having gastroenterology malignancy.
  • * patients on immunotherapy.
  • * HIV patients.

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Cairo, , Egypt

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0