Immunological Mechanisms Underlying Mucosal IgE Responses

Launched by UNIVERSITY HOSPITAL, GHENT · Jan 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the immune system's role in conditions like allergic asthma and late-onset eosinophilic asthma, which can cause issues in breathing and nasal congestion. The researchers aim to understand how a specific type of antibody called IgE is produced in these conditions, which could help explain why these diseases happen and how they can be treated better. They will also look at how a medication called Dupilumab works in this process.

If you have nasal polyps and are between the ages of 65 and 74, you might be eligible to participate in this study. However, if you have taken systemic corticosteroids in the last two months, you won't be able to join. Participants can expect to undergo various tests, including blood samples and other advanced techniques, to help uncover the mechanisms behind these asthma conditions. The findings from this trial could lead to new treatments that specifically target these types of asthma, providing hope for better management of these chronic diseases.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients with nasal polyposis -
• Exclusion Criteria:
• • patients treated in the last 2 months with systemic corticosteroids
• • -