Search / Trial NCT06234839

Lactobacillus Reuteri Strains for Gingivitis Reduction

Launched by UNIVERSIDAD AUTONOMA DE SAN LUIS POTOSÍ · Jan 30, 2024

Trial Information

Current as of October 07, 2024

Completed

Keywords

Gingivitis Lactobacillus Reuteri Bacteriotherapy Clinical Randomized Trial

Description

Aim. To investigate the potential beneficial effects in volunteer young adults of orally daily administered L. reuteri (DSM 17938 and ATCC PTA 5289) on gingival inflammation. The null hypothesis was that no difference would be manifested by probiotic therapy regarding the conventional mechanical treatment (without probiotic administration). Methods. A randomized controlled parallel clinical trial was conducted in sixty young adults (18-35 yrs old) with chronic marginal gingivitis for one month. Initially, both study groups underwent conventional mechanical periodontal therapy/oral anti-pla...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Non-smokers (at least for the last 6 months).
  • * Initial mean gingival index (GI) between 1.5 - 2.
  • * With a minimum of 20 teeth present in the oral cavity.
  • Exclusion Criteria:
  • * Periodontal pockets \> 4 mm.
  • * Recent intake of antibiotics or anti-inflammatory drugs and/or reception of dental prophylaxis.
  • * Daily consumption of analgesics, probiotics, or oral antimicrobial rinses/gels.
  • * Overweight (MCI \>25).
  • * Alcohol or recreative drug frequent consumers.
  • * Pregnancy or breast-feeding.
  • * Allergy or hypersensitivity to study products
  • * Fixed orthodontic appliances.

About Universidad Autonoma De San Luis Potosí

The Universidad Autónoma de San Luis Potosí (UASLP) is a prestigious higher education institution in Mexico, renowned for its commitment to advancing research and innovation in the biomedical field. With a strong emphasis on interdisciplinary collaboration, UASLP actively engages in clinical trials aimed at improving health outcomes and contributing to the scientific community. The university's experienced faculty and state-of-the-art facilities enable the execution of rigorous clinical research, fostering the development of new therapeutic approaches and enhancing the quality of patient care. Through its clinical trial initiatives, UASLP aims to bridge the gap between research and clinical practice, ultimately benefiting diverse populations and addressing pressing health challenges.

Locations

San Luis Potosi, , Mexico

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0