European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Jan 23, 2024

Keywords

ClinConnect Summary

The European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study is a research project that aims to better understand multiple and mixed heart valve diseases (MMVD), which occur when two or more heart valves are either narrowed (stenosis) or leaking (regurgitation). This study will take place at various centers around the world and will follow participants for one year, with a chance to extend the study up to five years. The main goal is to find out how common MMVD is among patients being evaluated for heart valve issues. Additionally, researchers will look at various characteristics of the disease, treatment approaches, and their effects on patient health over time.

To participate, individuals need to be at least 18 years old and have been referred for heart imaging tests that confirm they have MMVD. Specifically, participants should have moderate to severe issues in at least two different heart valves or have both narrowing and leaking in a single valve. Those with a history of certain heart surgeries or infections may not be eligible. If you join the study, you can expect to share your health information and undergo various assessments, which will help doctors learn more about how to diagnose and treat MMVD effectively. This important research aims to fill gaps in our understanding of heart valve diseases and improve care for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 18 years
• • 2. Patient referred to the cardiovascular imaging department.
• 3. Diagnosis of MMVD confirmed by transthoracic echocardiography, defined as:
• • 1. Multiple VHD: at least 2 moderates to severe VHD involving ≥ 2 different valves, using the current ESC guidelines.
• • and/or
• • 2. Mixed VHD: at least moderate stenosis and at least moderate regurgitation of a single valve, using the current ESC guidelines.
• • 4. Patient not refusing to have their data involved in the protocol after information.
• Exclusion Criteria (patients fulfilling any of the following criteria are not eligible for inclusion in this study):
• • 1. History of prior valve surgery or percutaneous valve intervention (concerning a valve other than those involved in the definition of MMVD).
• • 2. Acute infective endocarditis at the time of evaluation for inclusion (confirmed according to modified Duke criteria) or history of endocarditis ≤ 6 months.
• • 3. Complex congenital heart diseases.