Search / Trial NCT06236230

Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease

Launched by SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY · Jan 24, 2024

Trial Information

Current as of October 09, 2024

Recruiting

Keywords

Parkinson Disease Levodopa/Carbidopa/Entacapone

Description

This study will enroll subjects who have a diagnosis of PD with Hoehn-Yahr stage 1.5-3.0 and assess the impact of low dosage of levodopa/carbidopa/entacapone treatment on the motor function and quality of life among PD patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Male or female and greater from 30 to 80.
  • * Diagnosis of idiopathic PD according to the MDS PD Diagnostic Criteria (2015).
  • * Hoehn-Yahr stage of 1.5-3.0 ("open" stage).
  • * Not on anti-PD medication or stable on anti-PD medication for at least 30 days.
  • Exclusion Criteria:
  • * Diagnosis of atypical Parkinsonian syndrome, vascular Parkinsonism or drug-induced Parkinsonism.
  • * History of surgery within 6 months.
  • * Alcoholism, drug abuse, or severe cognitive impairment (including severe Alzheimer's disease)
  • * Psychiatric illness, epilepsy, pregnancy and breastfeeding, and clinically significant concomitant illnesses
  • * Participation in another clinical trial within 2 months.
  • * With dyskinesia.
  • * Any other condition that, in the opinion of the investigator, makes them ineligible for enrolment.

About Second Affiliated Hospital Of Soochow University

The Second Affiliated Hospital of Soochow University is a leading medical institution in China, renowned for its commitment to advanced healthcare and clinical research. As a prominent sponsor of clinical trials, the hospital leverages its extensive expertise in various medical fields to facilitate innovative treatments and improve patient outcomes. With a multidisciplinary team of experienced clinicians and researchers, the institution aims to contribute to the global medical community by advancing evidence-based practices and fostering collaborations that enhance therapeutic options. Through rigorous trial management and adherence to ethical standards, the Second Affiliated Hospital is dedicated to enhancing the quality of care and driving medical advancements.

Locations

Shanghai, Shanghai, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0