Search / Trial NCT06236451

Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia

Launched by ALL INDIA INSTITUTE OF MEDICAL SCIENCES, BHUBANESWAR · Jan 24, 2024

Trial Information

Current as of October 08, 2024

Recruiting

Keywords

Schizophrenia Mitochondrial Electron Transport Chain Complex Aripiprazole Risperidone Mitochondrial Dysfunction

Description

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Patients meeting the DSM-5 criteria for diagnosis of schizophrenia.
  • * Treatment naıv̈ e patients or patients who had not taken any antipsychotic drugs for at least 4 weeks before recruitment.
  • * Patients of either sex between the ages of 18 and 60 years.
  • * Legally authorized representative (LAR) of patients consenting to participate in the study by signing the informed consent form.
  • Exclusion Criteria:
  • * Patients diagnosed with other psychiatric disorders including schizoaffective disorder or schizophrenia with somatoform disorders.
  • * Highly agitated patients who need immediate indoor-based treatment.
  • * Patients with known mitochondrial disorders (MELAS, LHON, Leigh syndrome, KearnsSayre syndrome, MERRF etc.)
  • * Patients with history of comorbidities like cardiovascular, renal, hepatic, neurological, respiratory or endocrinal diseases or malignancies.
  • * Patients with history of substance abuse.
  • * Pregnant or lactating mothers.

About All India Institute Of Medical Sciences, Bhubaneswar

The All India Institute of Medical Sciences (AIIMS), Bhubaneswar, is a premier medical research and educational institution dedicated to advancing healthcare through innovative clinical trials and research initiatives. Established to provide high-quality medical education and comprehensive patient care, AIIMS Bhubaneswar focuses on developing cutting-edge treatments and therapies to address pressing health challenges in India and beyond. With a commitment to ethical research practices and collaboration with national and international partners, AIIMS Bhubaneswar plays a pivotal role in enhancing medical knowledge and improving patient outcomes through evidence-based practices.

Locations

Bhubaneswar, Odisha, India

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0