Search / Trial NCT06236620

Iron and Zinc Absorption in Flakes Derived From Sprouted or Hydrothermally Processed Wheat

Launched by KU LEUVEN · Jan 24, 2024

Trial Information

Current as of December 22, 2024

Not yet recruiting

Keywords

Iron Absorption Zinc Absorption Iron Bio Availability Zinc Bio Availability

ClinConnect Summary

The study is divided into the iron and zinc study. The iron study is a randomised double-blind crossover design. 26 participants will consume the three test meal types (control wheat flakes, flakes derived from sprouted wheat and flakes derived from hydrothermally processed wheat) spiked with a specific iron isotope at three consecutive days as breakfast. The length of the study will be 17 days. The iron isotope composition in the blood of the participants will be measured on day 1 and day 17 of the study.

The zinc study is a randomised crossover design with two different meals (control wh...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • BMI range 18.5-25.0 kg/m²
  • Regular diet with 3 meals a day (at least 5 times a week)
  • Exclusion Criteria:
  • Intake of vitamin and/or mineral supplements during and 2 weeks before the stud
  • Intake of antibiotics 3 months prior to the study
  • Intake of medicines that have an impact on the gastrointestinal tract during and 2 weeks before the study
  • Previous or current gastrointestinal (e.g. Crohn's disease), endocrine or eating disorders or other gastrointestinal history
  • Previous or current substance/alcohol dependence or abuse (\> 2 units per day/14 units per week)
  • Currently smoking (have smoked in the last 28 days) or willingness to smoke during the study period
  • Pregnant or lactating or wishing to become pregnant in the period of the study
  • Allergy or intolerance to wheat (coeliac disease, gluten sensitivity) or citric acid
  • Adherence to vegan or vegetarian diets or special diets (weight loss, gluten-free etc...)
  • Blood donation in the 6 months prior to the study

Trial Officials

Kristin Verbeke, Prof.

Principal Investigator

KU Leuven

About Ku Leuven

KU Leuven, a prestigious research university located in Belgium, is renowned for its commitment to advancing medical science and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, KU Leuven integrates cutting-edge research with clinical practice, facilitating the development of new therapeutic strategies and medical technologies. The institution's robust infrastructure and expertise in various fields, including biotechnology, pharmacology, and public health, position it as a leader in conducting high-quality clinical research that adheres to rigorous ethical standards and regulatory requirements. Through its clinical trials, KU Leuven aims to contribute significantly to the global biomedical landscape and enhance health outcomes for diverse populations.

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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