Search / Trial NCT06236789

Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer

Launched by YONSEI UNIVERSITY · Jan 24, 2024

Trial Information

Current as of October 07, 2024

Recruiting

Keywords

Castration Resistant Prostate Cancer Ifosfamide/Mesna Efficacy Safety

Description

1. Retrospective analysis of the treatment outcomes of patients with metastatic castration-resistant prostate cancer who who received ifosfamide/mesna will be conducted. 2. Information regarding demographics (age, gender, and etc.), disease status (stage, metastatic lesion, and etc.), treatment details (administered anticancer drugs, treatment response to drug, and disease progression with progression date), and survival (death with date of death) will be recorded. 3. Statistical method was applied to analyze the correlation between clinical indicators and survival rate.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. 19 years and older adult male
  • 2. Patients with histologically confirmed prostate cancer
  • 3. Castration-resistant prostate cancer
  • 4. ECOG 2 or less
  • 5. Patients with previous docetaxel exposure
  • 6. Patients with available PSA level
  • 7. Patients with evaluable disease based on RECIST 1.1
  • Exclusion Criteria:
  • 1. Patients with other primary cancers diagnosed within 3 years other than prostate cancer
  • 2. Patients with a history of organ transplantation
  • 3. Hormone sensitive prostate cancer
  • 4. ECOG 3 or higher
  • 5. Patients without previous docetaxel exposure
  • 6. Patients previously exposed to ifosfamide
  • 7. Patients without available PSA level
  • 8. Patients without evaluable disease based on RECIST 1.1

About Yonsei University

Yonsei University, a prestigious institution located in South Korea, is renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, Yonsei University leverages its extensive expertise and innovative approaches in various fields of medicine to conduct rigorous clinical trials aimed at improving patient outcomes and advancing healthcare solutions. The university's robust infrastructure, multidisciplinary collaboration, and adherence to ethical standards ensure the integrity and reliability of its research initiatives, making it a key player in the global clinical research landscape.

Locations

Seoul, , Korea, Republic Of

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0