Effect of Early Enteral Nutrition on Postoperative Recovery of Ovarian Cancer Patients

Launched by LUO CHENGYAN · Jan 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of nutrition after surgery can help women recover from advanced ovarian cancer. Specifically, it compares two methods: one involves feeding patients through a tube placed in the small intestine (called enteral nutrition), and the other provides nutrients through a vein (called parenteral nutrition). The goal is to see which method helps patients recover faster and improves their overall health after surgery to remove tumors.

To participate in this study, women aged 18 to 75 who have been diagnosed with advanced epithelial ovarian cancer and are scheduled for surgery may be eligible. Important factors include having tumors that affect areas outside the pelvis and not having certain medical conditions, like severe infections or heart problems. Participants can expect to be closely monitored during their recovery as the study looks at how early nutrition impacts healing. This study aims to provide insights that could improve care for future patients undergoing similar treatments.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • (1) The age is more than 18 years old and not more than 75 years old; (2) Ovarian cancer patients who are clearly diagnosed as epithelial ovarian cancer by pathological examination, whose tumors involve organs other than the pelvis as determined by preoperative imaging and intraoperative visual judgment, and who are at FIGO stage III or IV, and who undergo tumor cytoreductive surgery; (3) Patients without contraindication to nasoenteric tube placement and enteral nutrition; (4) Patients and their families were informed of the significance of the early use of enteral nutrition, precautions, adverse reactions, etc., before the operation, and they gave informed consent to this study and signed the informed consent; (5) Patients who received treatment in our hospital with complete clinical data.
• Exclusion Criteria:
• • (1) Patients with intestinal obstruction, severe intestinal infection, severe diarrhea, and acute abdomen right before surgery; (2) Patients with esophagogastric fundal varices and active gastrointestinal bleeding right before surgery; (3) Patients who undergo surgery to simultaneously resect the intestinal canal in the area more than 15cm distal to the ligament of Traitz; (4) Patients with severe cardiac, hepatic, and renal failure; (5) Patients with severe rhinitis, nasal mucous membrane damage, bleeding; (6) Patients with other malignant tumors combined within 3 months before surgery; (7) Metastatic ovarian cancer; (8) Those with missing clinical information; (9) Those with known hypersensitivity to enteral nutrition preparations.