Behavioral Exercise Training to Reduce Cardiovascular Disease Risk

Launched by VIRGINIA COMMONWEALTH UNIVERSITY · Jan 31, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring a new exercise program designed to help men with prostate cancer improve their fitness and reduce their risk of heart disease. The program involves home-based exercise training, which means you can participate from the comfort of your own home. Participants will be compared to a group that receives education on healthy living over a period of 12 weeks. The goal is to see if the exercise program helps improve how well participants can exercise, measured by how far they can walk in six minutes and their overall fitness levels.

To be eligible for this trial, you need to be a man aged between 40 and 85 who has been diagnosed with stage II, III, or IV prostate cancer and is currently receiving hormone therapy. You'll also need to have completed any local treatments like surgery or radiation. It's important that you can use a computer or smartphone to join the program and that you're comfortable with being recorded during interviews. If you have any serious heart conditions or other health issues, you may not be able to participate. This trial is a great opportunity for eligible patients to engage in a supportive exercise program while contributing to important research.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Be diagnosed with stage II/III/IV prostate cancer
• • Be currently undergoing treatment with ADT (intermittent or prolonged)
• • Have completed local curative-intent treatment, including prostatectomy or definitive radiation;
• • Be \>40 years of age up to 85;
• • Be willing to sign an informed consent with HIPAA authorization form;
• • Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation;
• • Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview;
• • Be without any serious medical condition that precludes safe participation in an exercise program;
• • Speak English
• Exclusion Criteria:
• • Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia);
• • Have contraindications to exercise testing;
• • Have pre-existing overt cardiovascular disease/heart failure;
• • Active illness/infection;
• • Hemoglobin \< 7.0 grams/dL
• • Platelet count \< 10 x 109/L