Melatonin on Anxiety and Sleep Quality in Adults Undergoing Coronary Artery Bypass Graft Surgery

Launched by AIN SHAMS UNIVERSITY · Jan 31, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how melatonin, a natural sleep aid, can help improve sleep quality and reduce anxiety in adults who are recovering from coronary artery bypass graft (CABG) surgery. The goal is to see if taking melatonin can also lessen the need for pain medication after surgery.

To be eligible for this trial, participants need to be between 40 and 60 years old and scheduled for standard CABG surgery performed by the same surgical team. However, certain individuals, such as those with allergies to the study drugs, those taking specific medications for mental health or sleep issues, or those with certain medical conditions like severe respiratory diseases or sleep disorders, won't be able to participate. If you join the study, you can expect to be monitored for how well you sleep and how anxious you feel after your surgery, helping researchers understand the potential benefits of melatonin for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age from 40-60 years.
• • Both sexes.
• • Patients undergoing standard on-pump CABG with the same technique by the same surgical team.
• Exclusion Criteria:
• • Refusal of procedure or participation in the study by patients.
• • Patients with known history of allergy to one of study drugs
• • Patients taking psychiatric medications, CNS depressants, and hypnotic drugs.
• • Patients with neurological disorders stroke, intracranial hemorrhage and surgery.
• • Patients with a history of suffering from any sleep disorder.
• • Severe circulatory or respiratory disease.
• • Patients with obstructive sleep apnea.
• • Cognitive or psychiatric illness that leads to inability to cooperate, speak or provide informed consent