The Quality of Recovery From General Anesthesia With Desflurane for Fundus Surgery

Launched by SICHUAN PROVINCIAL PEOPLE'S HOSPITAL · Jan 26, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different types of anesthesia for patients undergoing fundus surgery, which is a procedure related to the eye. The study will compare the effects of desflurane anesthesia mixed with remifentanil (a pain reliever) to another combination of sevoflurane anesthesia with remifentanil. The main goal is to understand how well patients recover after using desflurane and to help doctors make better choices about anesthesia in the future.

To participate in this trial, you need to be between 18 and 65 years old and healthy enough for surgery, with a body mass index (BMI) between 18 and 30. The surgery is expected to last about 30 to 120 minutes. However, certain health conditions, like severe heart or lung diseases, a history of asthma, or problems with drug or alcohol use, may prevent you from joining. If you decide to participate, you’ll be helping researchers learn more about how different anesthetics affect recovery, ultimately improving care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. ASA I-II, patients aged 18-65 years old;
• • 2. Fundus surgery to be performed under general anesthesia ;
• • 3. The expected duration of surgery is about 30-120 min ;
• • 4. BMI: 18-30 kg/m2 ;
• • 5. Those who signed the informed consent form and volunteered to participate in this trial
• Exclusion Criteria:
• • 1. Patients with known or suspected genetic susceptibility to malignant hyperthermia;
• • 2. Patients with history of asthma;
• • 3. Patients with severe heart diseases (NYHA ≥ III, severe arrhythmia, etc.) and cerebral or pulmonary diseases, liver or kidney dysfunction; or with unstable vital signs;
• • 4. Patients with history of long-term narcotic analgesics application, including sedative and antidepressant drugs;
• • 5. Patients with history of psychotropic drug abuse within 3 months;
• • 6. Patients with long-term alcohol abuse;
• • 7. People with mental disorder and unable to communicate normally;