The Impact of Sedation Depth Monitoring for Cognitive Functions and Early Rehabilitation After Major Joints Arthroplasty

Launched by LITHUANIAN UNIVERSITY OF HEALTH SCIENCES · Jan 28, 2024

Keywords

ClinConnect Summary

The aim: To determine value of sedation depth monitoring in order to save patients cognitive functions, to reduce incidence of postoperative delirium and to improve quality of early rehabilitation after the elective total elective knee replacement surgery.

Primary hypothesis: targeted sedation depth monitoring, in order to support light sedation level during the elective knee arthroplasty, helps to save cognitive function and reduce incident of postoperative delirium.

Secondary hypothesis: targeted sedation depth monitoring, in order to support light sedation level, provide better ability...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients undergoing elective total knee replacement surgery under spinal anesthesia with sedation;
• • Age 66 - 90 years;
• • Patients conformed to American Society of Anesthesiologists (ASA) physical status I-II in preoperative assessment;
• • Ability to follow study protocol;
• • Signed agreement to participate in the study.
• Exclusion Criteria:
• • Refused elective total knee arthroplasty under spinal anesthesia with sedation;
• • Younger than 66 years;
• • Patients conformed to American Society of Anesthesiologists (ASA) physical status III-IV in preoperative assessment;
• • Patients with mental and central nervous system disorders, which hinder the perception and correct assessment of their condition;
• • Hearing, visual, speech disorders and inability to read, write;
• • Inability to understand and read in Lithuanian language;
• • Refusal to participate in the study.