Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome

Launched by AFYONKARAHISAR HEALTH SCIENCES UNIVERSITY · Feb 5, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different methods to treat carpal tunnel syndrome, a condition that causes pain, numbness, and weakness in the hand due to pressure on the median nerve. The trial compares a technique called ultrasound-guided injection, which delivers medication directly around the nerve, with a surgical procedure that involves making a small cut to relieve pressure on the nerve. The goal is to see which method works better for patients with mild to severe symptoms.

To participate in this trial, individuals should be experiencing symptoms like nighttime pain or tingling in their hands for more than three months and have been diagnosed with carpal tunnel syndrome through specific tests. Eligible participants can be of any gender and are typically between the ages of 18 and 80. They can expect to receive either the injection or the surgery as part of the study and will help contribute to understanding which treatment might be more effective. It’s important to note that certain conditions, like previous surgeries or specific medical issues, will exclude some individuals from joining the trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The presence of symptoms such as nocturnal, posture-related, or movement-related paresthesias, along with possible pain, in the area supplied by the median nerve in the hand, lasting for more than 3 months.
• • Confirmation of mild, moderate or severe CTS through electrophysiological testing.
• • Numbness and loss of sensation in the hand's regions innervated by the median nerve, as well as weakness in the thenar muscles innervated by the median nerve.
• • Positive results on either the Phalen test and/or Tinel sign.
• Exclusion Criteria:
• • Individuals who may exhibit symptoms mimicking carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, or thoracic outlet syndrome.
• • Patients who have received a previous injection into the carpal tunnel within the past 6 months.
• • Thenar muscle atrophy.
• • A history of prior carpal tunnel surgery.
• • Regular usage of systemic nonsteroidal anti-inflammatory drugs and corticosteroids.
• • Pregnancy
• • Patients diagnosed with rheumatoid arthritis, systemic lupus erythematosus, gout, systemic sclerosis, dermatomyositis, or polymyositis.
• • Malignancy.
• • Active infections