Ultrasound Guided Autologous Blood Injection in Temporomandibular Joint Dislocation
Launched by CAIRO UNIVERSITY · Feb 2, 2024
Trial Information
Current as of November 13, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to treat people who frequently experience temporomandibular joint (TMJ) dislocations. The researchers want to see if using ultrasound to guide a treatment called autologous blood injection (where a patient's own blood is injected) is more accurate and effective than a method that doesn’t use ultrasound. The goal is to help reduce the number of dislocation episodes and improve the overall treatment process.
To participate, you need to be at least 18 years old and have had at least three TMJ dislocations in the past six months that required medical help to fix. Other criteria include having a specific range of mouth opening and no serious health issues that could interfere with the study. If you join, you can expect to receive care from trained professionals, and your progress will be monitored throughout the study. It's important to know that some people may not be eligible due to certain health conditions, but if you meet the criteria, this could be a chance to explore a potentially helpful treatment for your TMJ dislocations.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient with at least 3 episodes of temporomandibular joint dislocation in the past 6 months.
- • Necessitating a visit to the emergency room or trained professional to reduce the dislocation.
- • Radiological evidence of displacement of condylar head beyond the articular eminence on wide mouth opening.
- • Maximum mouth opening (MMO) more than 40 mm.
- • Unilateral or bilateral.
- • Over 18 years of age.
- • Both gender Males or females.
- Exclusion Criteria:
- • Patient having inflammatory temporomandibular joint disease like tuberculous arthritis, rheumatoid arthritis.
- • Patients with bleeding disorders, pregnancy or bony pathology of temporomandibular joint .
- • Allergy to local anesthetic.
- • Severe epilepsy or Parkinson's disease.
- • Patient on anti-depressants or anti-psychotics.
- • Inability to follow-up the patient during the entire follow-up period.
- • Patients who had recent fracture at temporomandibular joint level or who had previous surgical interference to temporomandibular joint .
- • Refused to sign the written informed consent were also excluded.
- • Dystonia
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported