A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging

Launched by HOSPICES CIVILS DE LYON · Feb 2, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating a new technology called magnetoencephalography (MEG), which is a non-invasive method to measure brain activity. The researchers want to see if this new type of MEG, which uses special sensors, can better detect brain activity in two groups: healthy volunteers and athletes who have recently experienced a mild concussion. They will be looking at how well this new device works compared to traditional MEG systems and whether it can create detailed maps of brain activity.

To participate in the trial, healthy volunteers must be between 18 and 70 years old and be motivated to take part. Athletes with a mild concussion need to be male and aged 18 to 40, with their concussion confirmed by a doctor. Participants will undergo tests that involve visual, sound, and movement stimuli while their brain activity is recorded. It's important to note that individuals with certain medical conditions or those who cannot undergo MEG or MRI examinations due to metal implants may not be eligible. Overall, this study aims to improve our understanding of brain function and how to better diagnose and treat concussions.

Gender

ALL

Eligibility criteria

• Healthy volunteers:
• Inclusion Criteria:
• • Age 18 to 70
• • Strongly motivated to participate to the study
• • Signed informed consent for the study
• Exclusion Criteria:
• • major cognitive deficit and unable to understand the instructions
• • previous neurology or psychiatric or sleep pathologies
• • Woman with a positive pregnancy test during the inclusion.
• • Subjects under guardianship, curatorship or safeguard of justice protection
• • Subjects deprived of their liberty
• • Subject not affiliated to a social security system.
• * Subject with common contraindications to MEG and MRI examination :
• • Metal in the body incompatible with performance of the examination (pacemaker, implantable pump, neurostimulator, cochlear implant, auditory prothesis, metalic prothesis, intracerebral clip, implantable defibrillator, any metalic parts in the brain or upper part of the body, ventriculoperitoneal valve, dental appliance or steel pivot for root canal, ferromagnetic foreign body in the upper part of the upper part of the body)
• • Claustrophobia
• Subjects who suffered a mild concussion:
• Inclusion Criteria:
• • Male aged from 18 to 40
• • Strongly motivated to participate to the study
• • Signed informed consent for the study
• • Mild concussion confirmed by the club doctor and a neurologist neurologist in the three weeks preceding the experiment
• Exclusion Criteria:
• • major cognitive deficit and unability to understand the instructions
• • previous neurology or psychiatric or sleep pathologies except mild concussion
• • Woman with a positive pregnancy test during the inclusion.
• • Subjects under guardianship, curatorship or safeguard of justice protection
• • Subjects deprived of their liberty
• • Subject not affiliated to a social security system
• * Subject with common contraindications to MEG and MRI examination :
• • Metal in the body incompatible with performance of the examination (pacemaker, implantable pump, neurostimulator, cochlear implant, auditory prothesis, metalic prothesis, intracerebral clip, implantable defibrillator, any metalic parts in the brain or upper part of the body, ventriculoperitoneal valve, dental appliance or steel pivot for root canal, ferromagnetic foreign body in the upper part of the upper part of the body)
• • Claustrophobia