Transcranial Direct Current Stimulation Combined With Oral Feeding on Dysphagia

Launched by ZENG CHANGHAO · Jan 31, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called transcranial direct current stimulation (TDCS) combined with oral feeding on patients who have difficulty swallowing after having a stroke, a condition known as dysphagia. The trial lasts for 15 days and involves patients who are receiving care at a rehabilitation department. Participants will be randomly assigned to either the experimental group, which receives the TDCS treatment along with standard rehabilitation and feeding support, or to a placebo group, which will receive the standard treatment but without any real effects from the TDCS device.

To be eligible for this trial, participants must be adults over 18 years old who have had their first ischemic stroke and have confirmed swallowing difficulties. They should be stable enough to participate and must be transferred to rehabilitation within 15 days of their stroke. Participants can expect to receive regular rehabilitation and support for their swallowing issues, and they'll be closely monitored throughout the study. It's important to note that those with certain medical conditions or who are pregnant won't be able to join the trial. This research aims to find out if adding TDCS can help improve swallowing function in stroke patients, which could lead to better recovery and quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Meet the diagnostic criteria for ischemic stroke;
• • Age \> 18 years;
• • First-time stroke;
• • Swallowing disorder confirmed by swallowing contrast study or flexible endoscopic evaluation of swallowing;
• • Requires enteral nutrition support;
• • Stable vital signs, no severe cognitive impairment or aphasia, able to cooperate with treatment;
• • Transferred to the rehabilitation department within fifteen days of onset; Stable vital signs.
• Exclusion Criteria:
• • Presence of contraindications for invasive oral endoscopy;
• • Concurrent presence of other neurodegenerative diseases that may cause swallowing disorders, such as neurodegenerative diseases;
• • Concurrent presence of other neurological disorders;
• • Tracheostomized patients;
• • Concurrent liver, kidney failure, tumor, or hematological disorders;
• • Pregnancy;
• • Presence of contraindications for transcranial direct current stimulation, such as epilepsy, cerebral edema;
• • Recent use of centrally acting drugs that interfere with the effects of transcranial direct current stimulation, such as carbamazepine, phenytoin, valproic acid, etc.