Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium

Launched by BAKULEV SCIENTIFIC CENTER OF CARDIOVASCULAR SURGERY · Feb 2, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods for treating atrial fibrillation (AF), a heart condition that can lead to serious issues like strokes. AF increases the risk of stroke significantly, making it very important to find effective treatments. The study will compare two techniques—radiofrequency and cryoablation—used to treat AF by targeting a specific area in the heart called the left atrium. Researchers want to learn which method works better and why some patients might experience a return of their AF after treatment.

To participate in this trial, you need to be at least 18 years old and have AF that hasn’t improved with other treatments. The study is open to anyone who meets these age and health criteria, but some individuals with certain heart conditions or other serious health issues may not be eligible. If you join the trial, you’ll receive one of the two treatment methods and will be monitored closely by the medical team. This is an important opportunity to contribute to research that could help improve care for others with AF in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 18 years old;
• • Atrial fibrillation resistant to antiarrhythmic therapy;
• • Persistent and long-persisting form of atrial fibrillation;
• • The patient's consent to participate in the study.
• Exclusion Criteria:
• • Age under 18 and over 80 years old;
• • The presence of another cardiac pathology requiring surgical treatment;
• • Congenital heart defects;
• • Previous "open" cardiac surgery;
• • Bone marrow diseases;
• • Pathology of the blood coagulation system;
• • The left ventricular ejection fraction is less than 40%;
• • Moderate to severe renal insufficiency (creatinine clearance \<50 ml/min);
• • Drug-resistant hypertension (despite hypotensive therapy);
• • Organically altered mitral valve;
• • There are reasons to assume that the patient will not show up for subsequent visits (control points of the study) for various reasons;
• • The patient's participation in another clinical trial.