Ciprofol EC50 for Inducing Loss of Consciousness in Elderly Patients

Launched by ZHEJIANG CANCER HOSPITAL · Feb 9, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new sedative drug called ciprofol, which is designed to help elderly patients safely lose consciousness before surgery. Researchers want to find out the best dosage of ciprofol for different age groups among patients aged 65 and older who are undergoing non-cardiac surgeries. Early results show that ciprofol is effective and may have fewer side effects compared to traditional sedatives, like propofol, making it an important option for elderly patients.

To be eligible for this trial, participants must be at least 65 years old and have a good overall health status (classified as ASA physical state I or II). They should not have any severe health issues or allergies to the study drugs. If you join, you will receive an initial dose of ciprofol based on your age, and the doctors will adjust it as needed during the procedure. The trial is currently recruiting participants, and all genders are welcome. Your involvement can help improve anesthesia safety and effectiveness for older adults in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 65 ≤ age years;
• • ASA physical state I and II;
• • Hadn't a history of allergy to the drugs used in this study;
• Exclusion Criteria:
• • America Society of Anesthesiologists (ASA) class \>III;
• • Allergic to anesthetic solutions or the drugs used in this study;
• • Body mass index (BMI) ≤ 20 or ≥ 30 kg/m2;
• • Using hypnotics, opioid analgesics, or anti-anxiety medications;
• • Known or suspected heart failure (ejection fraction \<40%), severe respiratory disease, renal or metabolic disease
• • Refuse to participate or participate with other clinical investigators ;