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Search / Trial NCT06253338

Optimization of Radiation Protection Through Genomic Analyses

Launched by UNIVERSITY HOSPITAL, ESSEN · Feb 7, 2024

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Dna Cancer Sequencing Technologies Lymphocyte Genomic Loosely Ionizing Radiation Linear Energy Transfer Outcome Thoracic Radiotherapy

ClinConnect Summary

This clinical trial is exploring how our genes respond to radiation exposure, particularly in people with thoracic (chest) or head and neck cancers. Researchers are using advanced technology to analyze genetic material to identify specific changes that can help understand how much radiation a person has been exposed to, the type of radiation, and how well their body can repair itself after exposure. The ultimate aim is to find ways to protect patients better during treatments that involve radiation.

To participate in this trial, you need to be between the ages of 65 and 74 and have been diagnosed with thoracic or head and neck cancer, but you should not have had any previous cancer treatments or diagnoses. If you qualify, you can expect to undergo genetic testing, which will help researchers gather important information about your individual response to radiation. This study is currently looking for participants, and it could play a vital role in improving radiation protection for future cancer treatments.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ECOG 0/1 no prior treatment no prior cancer diagnosis thoracic or head and neck cancer
  • Exclusion Criteria:
  • prior treatment (chemotherapy, radiotherapy, etc.) prior cancer diagnosis

About University Hospital, Essen

The University Hospital Essen is a leading academic medical center dedicated to advancing healthcare through innovative research and comprehensive clinical services. As a prominent sponsor of clinical trials, the hospital leverages its extensive expertise in various medical disciplines to facilitate cutting-edge studies aimed at improving patient outcomes. With a commitment to scientific excellence and patient safety, the University Hospital Essen collaborates with a network of researchers and healthcare professionals to explore new therapies and treatment modalities, contributing significantly to the field of medicine and enhancing the overall quality of care.

Locations

Essen, Germany / Nrw, Germany

Essen, , Germany

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported