Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery

Launched by FUJIAN MEDICAL UNIVERSITY · Feb 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how monitoring a specific nerve during thyroid surgery affects patients' voices after the operation. The researchers want to understand whether changes in the nerve signals during surgery can help predict how well a patient will speak afterward. They will analyze data from surgeries and recordings of patients’ voices to find any connections between these nerve signal changes and the quality of the voice post-surgery. The aim is to improve surgical techniques and outcomes for patients undergoing thyroid surgery, particularly those with thyroid cancer.

To participate in this study, you need to be between 20 and 60 years old and scheduled to have a specific type of thyroid surgery that includes removing part of the thyroid and lymph nodes. However, if you have had previous neck surgeries, certain voice disorders, or other specific health issues, you may not qualify. If you do take part, you can expect to have your voice monitored before and after the surgery, helping doctors learn more about protecting nerve function during these procedures and enhancing recovery for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 20-60 years old.
• • Planned conventional unilateral thyroid lobectomy + isthmus resection + central compartment lymph node dissection.
• Exclusion Criteria:
• • History of past head and neck surgeries.
• • Pronunciation system defect and disorder history.
• • History of vocal cord polyps or nodules.
• • History of upper respiratory tract infection in the 2 weeks before surgery or postoperative infection history.
• • History of neurological disorders.
• • Abnormalities in the throat.
• • Preoperative damage to throat morphology or motor function.
• • Preoperative functional voice or language disorders, noticeable hoarseness, or difficulty in pronunciation.
• • Pre- and postoperative laryngoscopic examination showing vocal cord paralysis and arytenoid joint dislocation.
• • Neurological disorders causing abnormal throat function.
• • Patient unable to cooperate with VHI (Voice Handicap Index) assessment and voice spectrum examination.