Function of Tamsulosin in Older Males Undergoing Surgery with Indwelling Catheter
Launched by EMORY UNIVERSITY · Feb 6, 2024
Trial Information
Current as of August 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how a medication called tamsulosin (often known by the brand name Flomax) can help older men who have to use a urinary catheter after surgery. Specifically, the trial is looking at whether tamsulosin can reduce issues like urinary retention, which is when a patient has trouble urinating after the catheter is removed, and urinary tract infections that can happen with catheters. These problems can cause discomfort and anxiety and may require additional procedures to relieve the situation.
To participate in this trial, men aged 50 and older who are scheduled for elective surgery (surgery planned in advance, not emergency surgery) may be eligible, as long as they are physically fit for the procedure. However, certain individuals, such as those with specific kidney issues or those already taking tamsulosin, cannot join. If you decide to participate, you can expect to take tamsulosin as part of the study and help researchers understand its effects on urinary issues after surgery, potentially benefiting future patients.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Planned for elective surgery for any reason (benign, malignant, or indeterminate lesion) with either an open or minimally invasive approach (hepatobiliary, pancreatic, and colorectal operations)
- • Male and age ≥50 years
- • Deemed physically fit for surgery
- Exclusion Criteria:
- • Inability to obtain informed consent
- • Age \<50 years
- • Female
- • Baseline creatinine \>1.5x upper limit of normal
- • Tamsulosin therapy as a home-medication
- • Procedure involving the prostate, bladder, ureters, or kidneys
- • Planned Foley catheter removal on the same day of surgery
- • Planned nasogastric tube retention on postoperative day 1
- • Individuals taking daily phosphodiesterase 5 (PDE5) inhibitors (due to the risk of symptomatic hypotension if given with tamsulosin)
About Emory University
Emory University, a leading research institution located in Atlanta, Georgia, is dedicated to advancing medical knowledge and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, Emory harnesses the expertise of its renowned faculty and state-of-the-art facilities to conduct cutting-edge research across various fields, including oncology, neurology, and infectious diseases. The university's commitment to ethical research practices and patient safety ensures that all clinical trials are designed to generate valuable data that can lead to significant therapeutic advancements. By fostering partnerships with local hospitals and community organizations, Emory strives to translate research findings into real-world applications, ultimately enhancing health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Patients applied
Trial Officials
Kenneth Cardona, MD
Principal Investigator
Emory University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported