ClinConnect ClinConnect Logo
Search / Trial NCT06259760

AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia

Launched by KAOHSIUNG MEDICAL UNIVERSITY CHUNG-HO MEMORIAL HOSPITAL · Feb 7, 2024

Trial Information

Current as of August 21, 2025

Recruiting

Keywords

Acute Kidney Injury Orthognathic Surgery General Anesthesia Prospective Analysis Intentional Hypotension

ClinConnect Summary

This clinical trial is studying how using certain medications to lower blood pressure during general anesthesia affects kidney health in patients undergoing jaw surgery. The researchers want to find out if this approach can lead to kidney injury, specifically a condition called acute kidney injury (AKI). By closely monitoring blood tests and urine throughout the surgery, they aim to identify early signs of possible kidney problems. Recognizing these signs quickly can help doctors take action to prevent any kidney damage and support a quicker recovery for patients after surgery.

To participate in this trial, you need to be an adult aged 18 and older who is classified as low to moderate risk for anesthesia and is having specific jaw surgery. However, certain health issues, like severe obesity, liver problems, or uncontrolled diabetes, may exclude you from participating. If you join the study, you can expect regular health checks before, during, and after your surgery to ensure your kidneys are functioning well. This trial is currently recruiting participants and aims to improve recovery for surgical patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • America society anesthesiologist classification class I to II patients undergoing oro-maxillo-facial surgery
  • unlimited mouth opening
  • Exclusion Criteria:
  • patients with arthritis with limited mouth opening
  • persistent liver dysfunction
  • chronic renal insufficiency
  • body mass index ≧35 kg/m2.
  • past history of malignant hyperthermia or personal or family history
  • diabetes with insulin treatment
  • essential hypertension without controlled

About Kaohsiung Medical University Chung Ho Memorial Hospital

Kaohsiung Medical University Chung-Ho Memorial Hospital is a leading healthcare institution in Taiwan, dedicated to advancing medical research and improving patient care through innovative clinical trials. As a prominent sponsor, the hospital leverages its extensive expertise in various medical disciplines, state-of-the-art facilities, and a multidisciplinary team of professionals to conduct rigorous clinical studies. Committed to ethical standards and patient safety, the hospital collaborates with academic institutions and industry partners to facilitate groundbreaking research that contributes to the global medical community and enhances treatment options for diverse patient populations.

Locations

Kaohsiung, , Taiwan

Kaohsiung, Sanmin Dist, Taiwan

Patients applied

0 patients applied

Trial Officials

Kuang-I Cheng, Phd

Principal Investigator

Kaohsiung Medical University Chung-Ho Memorial Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported