Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Launched by COLORADO STATE UNIVERSITY · Feb 7, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to understand how alcohol and cannabis affect the brain differently, as well as how they work together when someone uses both substances. Researchers will use a special tool called electroencephalography (EEG) to measure brain activity, along with other common tests to check how intoxicated a person is. If you are between 21 and 50 years old, are a heavy drinker, and regularly use cannabis, you may be eligible to participate.

Participants will spend time in a mobile lab where they can use either alcohol, cannabis, or both, in a safe environment. The study seeks individuals who have used alcohol and cannabis together at least once a month in the last three months and who speak English. It's important to note that pregnant or breastfeeding women, daily tobacco users, and those with certain mental health or substance use disorders cannot participate. This study aims to gather valuable information that could help improve understanding of substance use and its effects.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 21-50 years old
• • Heavy drinkers (consuming more than 4 drinks/day or more than 14 drinks/week for men, or more than 3 drinks/day or more than 7 drinks/week for women)
• • Regular users of legal-market flower cannabis (at least 2x/week in past 3 months)
• • report simultaneously using alcohol and legal-market flower cannabis at least once per month in the past 3 months
• • English speakers.
• Exclusion Criteria:
• • Daily tobacco users
• • Diagnosed with or seeking treatment for alcohol use disorder (AUD) or other substance use disorder (SUD)
• • Females cannot be pregnant, breastfeeding or trying to become pregnant
• • Meet criteria for psychotic, bipolar or major depressive disorder with suicidal ideation, or history of these disorders, 5) Current use of psychotropic (except anti-depressants)
• • Report illicit drug use in past 60-days or fail drug screen on the day of the study appointment
• • Major medical condition contraindicating alcohol and/or cannabis consumption.