Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa

Launched by UNIVERSIDAD COMPLUTENSE DE MADRID · Feb 7, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different surgical techniques to improve the tissue around dental implants. Specifically, it compares a method using a combination of a strip graft (a piece of gum tissue taken from elsewhere in the mouth) with a special matrix that helps tissue grow, against a method using only a free gingival graft (gum tissue taken from another part of the mouth). The goal is to see which method better increases the amount of keratinized mucosa, which is the tough gum tissue around the implant. This study will also look at how well blood flows to the areas involved in the grafting and other factors like tissue thickness and patient satisfaction.

To participate in this trial, patients need to be over 18 years old and have dental implants in the lower jaw that do not have enough keratinized mucosa (less than 2 mm). They should be in good overall health, without any major health issues, and should not be heavy smokers or using certain medications. If you join, you can expect to undergo a surgical procedure and will be monitored for recovery and results, contributing to important research that could improve future dental surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients older than 18 years
• • Short-span dental implants in the mandible at second stage with inadequate PIKM (\<2 mm) with at least one adjacent tooth mesially
• • Periodontally healthy patients with a pristine or reduced periodontium
• • Plaque index (FMPS) less than 20%.
• Exclusion Criteria:
• • Compromised general health status that contraindicates study procedures (≥ASA III);
• • Drug or alcohol abuse;
• • Smoking of \> 10 cigarettes per day;
• • Chronic use of corticosteroids, NSAIDs or immunomodulators (any type or dose);
• • Pregnant or lactating women;
• • History of previous mucogingival surgeries in the area of interest