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Search / Trial NCT06261762

Hard and Soft Tissue Dimensional Change After Consecutive Extractions and Unassisted Socket Healing in the Esthetic Zone

Launched by SHANGHAI NINTH PEOPLE'S HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY · Feb 7, 2024

Trial Information

Current as of August 19, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is studying what happens to the bone and soft tissue in the mouth after people have two teeth removed in the front part of the upper jaw, known as the anterior maxilla. Specifically, researchers want to find out if there is a significant loss of bone in the area where the teeth were removed and if this loss varies depending on where the teeth were located. They will also look at changes in the thickness of the soft tissue and the height of the gum tissue after the extractions.

To participate in this study, you need to be at least 18 years old and require two consecutive teeth extractions in the front of your mouth. You should also be in good general health and have healthy gums. Participants will have their extractions done and then will be observed for about 8 weeks to see how the area heals on its own without any special treatment. This research aims to help improve future dental procedures and patient care in similar situations.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18+ years old
  • Require consecutive (two) teeth replacement in the anterior maxilla
  • Signed informed consent
  • No significant medical conditions
  • Patients with healthy periodontal conditions or previously treated to controlled and stable conditions
  • Exclusion Criteria:
  • General medical (American Society of Anesthesiologists, ASA, class III or IV) and/or psychiatric contraindications
  • Pregnancy or nursing
  • Any interfering medication such as steroid therapy or bisphosphonate therapy
  • Uncontrolled diabetes
  • Autoimmune diseases or inflammatory diseases affecting the intraoral tissues
  • Radiation therapy to head or neck region

About Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

Shanghai Ninth People's Hospital, affiliated with Shanghai Jiao Tong University, is a leading clinical research institution in China, renowned for its commitment to advancing medical science and improving patient care. As a prominent teaching hospital, it integrates high-quality clinical services, innovative research, and comprehensive medical education. The hospital is dedicated to conducting rigorous clinical trials across various medical fields, leveraging its state-of-the-art facilities and a multidisciplinary team of experts to foster the development of new therapies and contribute to global health advancements.

Locations

Patients applied

0 patients applied

Trial Officials

Feng Wang

Principal Investigator

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported