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Search / Trial NCT06262126

Virtual Reality for Non-cardiac Chest Pain

Launched by MAYO CLINIC · Feb 8, 2024

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Virtual Reality

ClinConnect Summary

This clinical trial is exploring whether virtual reality (VR) can help improve symptoms for people experiencing non-cardiac chest pain (NCCP), which is chest pain that isn't caused by heart issues. The study is currently recruiting participants aged between 65 and 74 who have had chest pain that feels similar to angina but has been confirmed not to be related to heart problems through tests like an electrocardiogram. To join the trial, participants must also have had certain tests to rule out severe digestive issues.

If you qualify and choose to participate, you will use a VR headset during the study sessions, which will be designed to help reduce your chest pain symptoms. It’s important to note that individuals currently taking certain medications for stomach issues, have significant other health problems, or experience dizziness that could make using the VR headset difficult will not be able to participate. This trial aims to find out if this innovative approach can bring relief to those suffering from NCCP.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Symptoms of non-cardiac chest pain (recurrent anginal-like or atypical chest pain)
  • Negative prior cardiac evaluation (at a minimum, including electrocardiogram)
  • Prior esophagogastroduodenoscopy and/or barium esophagram to rule out severe esophagitis, stricture, or motility abnormality
  • Exclusion Criteria:
  • Initiation of a proton pump inhibitor (PPI) within 8 weeks
  • Major concomitant illness
  • Current drug or alcohol use that that would interfere with adherence to study requirements
  • Symptoms of vertigo or dizziness that would limit tolerability of the VR headset

About Mayo Clinic

Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.

Locations

Jacksonville, Florida, United States

Patients applied

0 patients applied

Trial Officials

Andree Koop, MD

Principal Investigator

Mayo Clinic

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported