Wound Management Following Gl Tumor Surgery: Comparing Outcomes of Dressing Changes Versus Non-Dressing Techniques

Launched by FUDAN UNIVERSITY · Feb 8, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how to best care for wounds after surgery for gastrointestinal tumors, which include cancers of the stomach, colon, and rectum. Researchers want to find out if leaving the surgical wounds exposed (non-dressing) is just as good or even better than using traditional dressings that need to be changed regularly. They will also see if the non-dressing method can help reduce pain and lower healthcare costs for patients.

To participate, you need to be 75 years old or younger and have a confirmed diagnosis of a gastrointestinal tumor. You should be scheduled for surgery to remove the tumor or to perform an open bypass surgery. If you join the study, you’ll be randomly assigned to either the exposed wound group or the dressing group. The study will check how well your wound heals, your pain levels, and any costs related to your care. This research aims to improve how we manage wounds after surgery, which could lead to better outcomes for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≤ 75 Years: Participants must be 75 years old or younger.
• • 2. Pathologically Confirmed Gastrointestinal Tumor: All participants must have a pathological diagnosis of a gastrointestinal tumor, including but not limited to stomach, colon, and rectal cancers.
• • 3. Undergoing Curative Surgery for Gastrointestinal Tumor or Open Gastrointestinal Bypass Surgery: Eligible for inclusion are those scheduled for curative resection or necessary open bypass surgery of the gastrointestinal tract.
• • 4. ECOG Performance Status 0/1: Participants should have an ECOG (Eastern Cooperative Oncology Group) performance status score of 0 or 1, indicating they are fully active or restricted in physically strenuous activity but ambulatory and able to carry out light or sedentary work.
• • 5. Able to Understand and Sign Informed Consent: Participants must be capable of understanding the written informed consent and willing to sign it.
• Exclusion Criteria:
• • 1. Unable to Complete Postoperative Follow-up: Patients who are unable to comply with the required postoperative follow-up.
• • 2. Ineligible for Surgical Treatment: Patients who are not candidates for surgical intervention.
• • 3. Concurrent Skin Disease: Patients with skin diseases that could affect wound healing, such as psoriasis or eczema.
• • 4. History of Abdominal Trauma or Surgery Leading to Deformity or Scar Formation: Patients with a history of abdominal trauma or previous surgery that resulted in deformity or significant scarring.
• • 5. Severe Uncontrolled Comorbid Conditions: Patients with severe, uncontrolled comorbid conditions, including but not limited to other active cancers, acute infections, or chronic unhealed infections.
• • 6. Currently Undergoing Other Cancer Treatments: Patients who are receiving any other form of cancer treatment, including chemotherapy, radiation therapy, biological therapy, or immunosuppressive therapy.
• • 7. Use of Steroids or Other Medications Affecting Wound Healing: Patients currently using steroids or other medications that might interfere with wound healing.