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Search / Trial NCT06267118

Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis

Launched by COMBINED MILITARY HOSPITAL, PAKISTAN · Feb 18, 2024

Trial Information

Current as of July 13, 2025

Recruiting

Keywords

Wood Downes Clinical Scoring System

ClinConnect Summary

This clinical trial is studying how well two different treatments work for children with acute bronchiolitis, which is a common respiratory infection caused by the Respiratory Syncytial Virus (RSV). The researchers want to compare hypertonic saline, a type of salt water solution, with adrenaline, which is a medication that can help open the airways. The main goals are to see how much each treatment helps improve breathing and to find out how long children need to stay in the hospital.

To participate in this trial, children must be admitted to the Pediatric Intensive Care Unit (PICU) with a diagnosis of acute bronchiolitis. However, children with certain other health conditions, like heart problems or infections that affect the brain or lungs, cannot take part. If your child is eligible, they will receive one of the treatments and doctors will closely monitor their progress. This study is currently recruiting participants, and it aims to provide important information that could help improve care for children with bronchiolitis in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All children admitted in PICU with acute bronchiolitis
  • Exclusion Criteria:
  • children with co-exiting illnesses like
  • 1. Congenital Heart Disease
  • 2. Immunodeficiency
  • 3. other Infectious disease like Meningitis, encephalitis, Pneumonia, TORCH
  • 4. Kidneys or liver problem
  • 5. Seizures

About Combined Military Hospital, Pakistan

The Combined Military Hospital (CMH) in Pakistan is a premier healthcare institution dedicated to providing advanced medical services and fostering innovative research in the field of military and civilian healthcare. As a leading clinical trial sponsor, CMH is committed to enhancing medical knowledge and improving patient outcomes through rigorous clinical research protocols. The hospital boasts a team of experienced professionals, state-of-the-art facilities, and a robust ethical framework, ensuring the highest standards of safety and compliance in all clinical trials. CMH's strategic focus on collaboration and excellence positions it as a key player in the advancement of medical science and therapeutic development in Pakistan and beyond.

Locations

Nowshera, Kpk, Pakistan

Patients applied

0 patients applied

Trial Officials

Prof Shahid Mahmud

Study Director

Military Hospital Rawalpindi

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported